Browsing Thesis (Bachelor of Science in Biotechnology) by Title
Now showing items 100-119 of 231
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In silico design of a multi-epitope vaccine against Lyssavirus Phylogroup II Glycoproteins
(Brac University, 2022-12)The genus of lyssavirus, coming from the family of Rhabdoviridae, has been around since the time of 2300 BC. A ~12kb, negative-sense RNA virus, it is known to be one of the lethal viruses ever encountered by mankind. ... -
In silico drug designing against Klebsiella pneumoniae adhesin protein
(Brac University, 2019-01)Klebsiella pneumoniae, is one of the causative agents of many nosocomial infections. In spite of having a plethora of information on the virulent factors of this bacteria, no definite vaccines have yet been designed or ... -
In Silico Epitope based peptide vaccine designing against yellow fever virus
(BRAC University, 2017-08)The most widely used vaccine for treatment of Yellow Fever patients is YF 17D. It is a live attenuated vaccine derived from Asibi strain. It is administered widely to patients throughout the world but it has few problems ... -
In silico identification of molecular mimicry between T-cell epitopes of borrelia burgdorferi and the human proteome: implications for autoimmune response in Lyme disease
(Brac University, 2022-12)Autoimmune disorder is a dysfunctional immune system in a body, which attacks its own cells. Borrelia burgdorferi, a pathogenic bacterium, shares an intrinsic relation to Lyme disease in humans causing autoreactive responses ... -
In silico modelling and structural dynamics of PSY1R kinase domain and its interaction with SERK1 kinase
(Brac University, 2021-09)Due to plants’ immobility, they are continuously faced with different challenges from their surroundings that also include a wide range of pathogens dealing in the environment. Hence by unraveling the mystery behind how ... -
In silico structural analysis of the complex BRI1 Receptor like Kinase, Pamp Brassinolide and Serk1 Co-Receptor
(Brac University, 2021-04)Plants that are sessile species are constantly associated with exposure to pathogenic organisms abundant in their biosphere. Comprehending the hypothesis next to it would be a significant attempt to study the processes ... -
In Silico structural analysis of the complex PSKR receptor like Kinase, Pamp Phytosulfokine and SERk1 co-receptor
(Brac University, 2021-02)Plants often have to undergo pathogen invasions in nature. Nevertheless, as a result of proficient immune systems owned by the host plants, plant diseases seldom occur. In the process two separate recognition mechanisms ... -
In silico structural analysis, physicochemical characterization and homology modeling of Arabidopsis thaliana Na+/H+ exchanger 1 protein
(BRAC University, 2015-09)Climate changes have detrimental effects on the plants such as an increased susceptibility towards pathogens or ill health leading to food insecurity. This is eminently observed in developing countries such as Bangladesh. ... -
In silico structural analysis, physicochemical characterization and homology modeling of Arabidopsis thaliana Na+/H+ exchanger 2 protein
(BRAC Univeristy, 2017-05)Along with climate change, salinity has a detrimental effect on plants. It can cause susceptibility towards pathogens, halt proper growth and thus lead to food insecurity. Therefore, it is necessary to comprehend the ways ... -
In silico structural analysis, physicochemical characterization and homology modeling of transmembrane protein 43 (TMEM 43)
(BRAC University, 2017-09)Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare disease of the heart muscle. ARVC is an inherited condition, which means that it is passed on through families. It is caused by a change or mutation in one ... -
In silico structural and functional analysis of cobra snake venom component- Kaouthiagin
(BRAC University, 2017-02)Snake venoms have been gaining a lot of attention in research, which has provided not only new tools to decipher molecular details of various physiological processes, but also the inspiration to design and develop many ... -
In silico structural and functional analysis of phospholipase D from brown recluse spider (Loxoceles reclusa) venom
(BRAC University, 2017-06)Spiders are an interesting class of insects - omnipresent in almost in all environment and vet, mostly remains unnoticed. They are carnivores in nature, relying on their own venom to neutralize their prey. There are many ... -
In silico T-cell epitopebased vaccine designing against Mycobacterium tuberculosis
(BRAC University, 2018-09)Mycobacterium tuberculosis is an obligate pathogenic bacterial species in the family Mycobacteriaceae and the causative agent of tuberculosis. At present BCG, an attenuated strain of Mycobacterium bovis is used as a ... -
In vitro antimicrobial, antihemolytic potential of gallic acid and its combined effect with metronidazole against pathogenic bacteria
(Brac University, 2022-11)Multidrug-resistant (MDR) or extensive drug-resistant (XDR) pathogenic bacteria pose a grave threat to human and animal health on a global scale. Plant-derived phytochemicals including alkaloids, flavonoids, and terpenoids ... -
In vitro collateral sensitivity: a potential approach against multiple antibiotic resistant bacteria
(Brac University, 2023-07)Antimicrobial Resistance (AMR) has long been recognized as a major issue. With the emergence and rapid spread of antibiotic-resistant bacteria, the world's stock of viable antibiotics is rapidly depleting. In this regard, ... -
In vitro culture establishment from Cotyledon and Embryonic Axis Explants of two Bangladeshi Sunflower (Helianthus annus L.) varieties
(BRAC University, 2015-03)Sunflower is considered as source of cholesterol free edible oil. Because of cross pollinating nature of this plant, it is difficult to identify true breeding homozygous line, thus, breeding becomes intricate. Besides, ... -
IN VITRO culture establishment from hypocotyl and cotyledon explants of two Bangladeshi sunflower (Helianthus annuus L. ) varieties
(BRAC University, 2015-03)Sunflower (Helianthus annuus.L) is the world’s second most important oilseed crop. Plant tissue culture and gene transformation are the important tools for improvement of this crop. The purposes of this study are to optimize ... -
Incidence, molecular characterization and antibiotic resistance profile of Methicillin resistant staphylococcus aureus Isolated from clinical origin and associated surroundings in hospital
(Brac University, 2019-10)Methicillin-Resistant Staphylococcus aureus (MRSA) is notorious for its resistance to Penicillin derivative antibiotics and is also resistant to multiple drugs. In Bangladesh, the prevalence of MRSA is a staggering 72%. ... -
Industrially beneficial microbes from kitchen waste: A green approach to produce Cellulase Enzyme and optimization of culture condition
(Brac University, 2022)Bacterial cellulases nowadays have been gaining considerable attention due to its enormous use in biotechnology. The study here was pursued with the aim to isolate cellulolytic bacterial strains from kitchen wastes ... -
Influence of heat shock and osmotic stresses on the growth and viability of Candida shehatae var shehatae and explore its probiotic potentiality
(Brac University, 2020-01)Live microorganisms with health benefits termed as probiotics, commercialized in the market to provide the health benefits to host. However, most probiotics are bacteria but very recently Saccharomyces boulardii, a yeast ...