Browsing Thesis (Bachelor of Science in Biotechnology) by Title
Now showing items 81-100 of 222
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Genetic disorders associated with mutations in bHLH transcription factors: a review
(Brac University, 2022-11)bHLH proteins belong to a superfamily of proteins characterized by one of the largest dimerized transcriptional proteins. The main role of bHLH protein is in the developmental processes. They function as transcriptional ... -
Genetics of Monogenic Kidney Stone Disease (KSD): A review
(Brac University, 2022-03)Kidney stone disease (KSD) is a multifactorial illness characterized by a complex combination of hereditary and environmental variables. It generates enormous morbidity and medical care costs all over the globe. The ... -
Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method
(Brac University, 2020-08)Pharmacogenetics is the study of how similar drugs affect different people differently according to their unique genetic makeup as an individual. Pharmacogenetics includes a wide variety of research and discovery ... -
Hematological analysis of anemic severity in beta thalassemia
(BRAC University, 2018)Beta thalassemia is an inherited blood disorder that affects synthesis of the beta chain in the production of haemogoblin, leading to the production of deficient RBCs (red blood cells) that cannot effectively transport ... -
Horizontal gene transfer: an insight into antimicrobial resistance
(Brac University, 2022-10)Antimicrobial resistance (AMR), which affects a variety of infectious pathogens, is a pivotal public health issue for many countries and corporations. Governments across the globe are starting to take heed of an issue ... -
Horizontal transfer of antibiotic resistance between trans-gram bacteria in surface water of Dhaka city
(Brac University, 2019-10)A global medical crisis has already started as antibiotics have started losing their effectiveness against the growing number of bacterial pathogens. Horizontal Gene Transfer (HGT) system has a great impact on this spreading ... -
Horizontal transfer of antibiotic resistance in surface water of Dhaka City
(Brac University, 2019-05)Horizontal gene transfer is one of the most widespread phenomenon by which bacteria evolve themselves in the environment. Such transfer is often reported to be responsible for spreading antibiotic resistance genes in nature. ... -
Impact of sunlight on chloramphenicol mediated synthetic and herbal eye drops in terms of antimicrobial activity
(BRAC University, 2017-12)Ocular bacterial infections can cause several eye diseases that have potential impact on human health which is a growing concern worldwide. The use of chloramphenicol synthetic eye drops could provide immense coverage ... -
Implications of unusual non-coding RNAs in human diseases
(Brac University, 2020)Over the last few decades, the occurrences of genetic diseases and the rationale behind them are still under the wheels of research. Researchers have unveiled various causes of genetic disorders and shed light on the ... -
Importance of antigen detection for the screening of COVID-19
(Brac University, 2020-10)Since the beginning of the COVID-19 pandemic, laboratories have been using nucleic acid amplification tests, such as real time reverse transcription polymerase chain reaction (rRT-PCR) assays, to detect SARS-CoV-2, the ... -
In planta transformation of three Bangladeshi tomato varieties with a vacuolar antiporter
(BRAC Univeristy, 2017-04)Salinity is one of the major obstructions in Bangladesh towards achieving maximum crop production. Being a consequence of climate change, soil salinity has rapidly increased over the years without any remedy in sight. Along ... -
In silico analysis of structural complex of HAESA receptor like kinase with PAMP IDA and SERk1 co-receptor
(Brac University, 2019-12)Pattern Triggered Immunity (PTI) is actually identified by the activities of pattern recognition receptors (PRRs), which play the most important role in first layer of plant defense mechanism. During aggression of microbes, ... -
An in silico approach for the identification of clinically significant SNPs in a Drug Metabolizing Gene CYP2C9 and development of Tetra-primer ARMS PCR based genotyping method for CYP2C9*3 (rs1057910)
(Brac University, 2020-08)The role of SNP is an important factor related to drug metabolism. The presence or absence of SNP can significantly alter the effect of the same amount of drug inside the body leading to various unwanted side-effects which ... -
An in Silico approach to multi-epitope subunit vaccine development against SARS COV-2 using Membrane Glycoprotein
(Brac University, 2020)SARS Cov -2, short for Severe Acute Respiratory Syndrome Coronavirus-2 is a + sense zoonotic retrovirus of the Coronaviridae family and is genetically a mutant version of the SARS Cov and is the causal organism of the ... -
In silico comparative study of Zika Virus Proteins and analysis of Membrane glycoprotein M as a candidate for vaccine design
(BRAC Univeristy, 2018-07-26)Zika virus is a (+) RNA virus that has become a major concern of public health in the last few years. It is known to cause microcephaly, reduction of brain circumference along with many type of brain injury in new-borns ... -
In silico design of a multi-epitope vaccine against Lyssavirus Phylogroup II Glycoproteins
(Brac University, 2022-12)The genus of lyssavirus, coming from the family of Rhabdoviridae, has been around since the time of 2300 BC. A ~12kb, negative-sense RNA virus, it is known to be one of the lethal viruses ever encountered by mankind. ... -
In silico drug designing against Klebsiella pneumoniae adhesin protein
(Brac University, 2019-01)Klebsiella pneumoniae, is one of the causative agents of many nosocomial infections. In spite of having a plethora of information on the virulent factors of this bacteria, no definite vaccines have yet been designed or ... -
In Silico Epitope based peptide vaccine designing against yellow fever virus
(BRAC University, 2017-08)The most widely used vaccine for treatment of Yellow Fever patients is YF 17D. It is a live attenuated vaccine derived from Asibi strain. It is administered widely to patients throughout the world but it has few problems ... -
In silico identification of molecular mimicry between T-cell epitopes of borrelia burgdorferi and the human proteome: implications for autoimmune response in Lyme disease
(Brac University, 2022-12)Autoimmune disorder is a dysfunctional immune system in a body, which attacks its own cells. Borrelia burgdorferi, a pathogenic bacterium, shares an intrinsic relation to Lyme disease in humans causing autoreactive responses ... -
In silico modelling and structural dynamics of PSY1R kinase domain and its interaction with SERK1 kinase
(Brac University, 2021-09)Due to plants’ immobility, they are continuously faced with different challenges from their surroundings that also include a wide range of pathogens dealing in the environment. Hence by unraveling the mystery behind how ...