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Targeted drug delivery using polymeric nanoparticles for the treatment of cancer: a review
(BRAC University, 2017-05)
Advances in the field of polymeric nanoparticles is rapidly progressing and offers new opportunities for targeted treatment of cancer. The targeted delivery of nanoparticles can overcome the problems associated with the ...
SHP2 inhibitors: Recent advancements and potential breakthroughs in cancer therapy
(Brac University, 2022-03)
SHP2 (Src homology-2 domain-containing protein tyrosinephosphatase-2) works as a tyrosine
phosphatase, to eliminate tyrosine phosphorylation in the non-receptor protein to link many
oncogenic signaling pathways including ...
A comprehensive bioinformatics analysis of BRAF in cancer
(Brac University, 2021-09)
BRAF is one of the most vital serine/ threonine-protein kinase proto-oncogenes that performs a crucial role in cellular proliferation, growth, signaling and secretion. By deregulation of this gene can lead to terrible ...
Role of statins as antagonists of SPARC in gastric cancer
(BRAC University, 2018-09)
Cancer refers to the abnormal and uncontrollable growth of cells in the body. It is the second leading cause of death in the world and in 2015 alone claimed the lives of 8.8 million people. The protein SPARC (Secreted ...
The role of cryo-electron microscopy in anticancer drug discovery and development
(Brac University, 2021-04)
Multidrug resistance in cancer treatment is one of the major causes of the increasing need for newer, potent, and safer anticancer drugs. The discovery and development of novel anticancer drugs are limited by the limitations ...
A review on less explored plants with anticancer activity
(Brac University, 2020-03)
Cancer is a disorder that is very complicated. Most tumors tend to be incurable. However,
appropriate measures can reduce the risk of cancer. Cancer is a very costly illness to manage
in a low-income nation such as ...
A review paper on Nanotechnology based strategies in the treatment of cancer
(Brac University, 2022-02)
Nanotechnology is a new discipline meeting the requirement for novel methods in cancer
treatment. Recently, cancer became very fatal condition that causes death worldwide. Hence,
traditional cancer treatment like ...
Antihypertensive drugs and risk of cancer: A pharmacovigilance study
(BRAC University, 2017-08)
Antihypertensive drugs are widely used for the treatment of hypertension, heart failure and, recently, for cardiovascular risk reduction. Experimental studies implicate antihypertensive drugs in the regulation of cell ...
A review on non-polyphenolic and terpenoid phytoconstituents with antioxidant and cytotoxic potential
(Brac University, 2020-03)
Plants with antioxidant and cytotoxic activity possess wide number of different
phytoconstituents such as tocopherol, polyphenolic compounds, flavonoids, ascorbic acid etc.
However, plants having non-polyphenolic compounds ...
Potential of nanoparticles as a topical drug delivery system for skin cancer: a review
(Brac University, 2022-07)
Skin cancer is among the most widespread and challenging forms of cancer, with high death rates globally, the seventeenth most prevalent cancer in the world. Conventional treatment options for skin cancer, including surgical ...