dc.contributor.advisor | Kabir, Md. Tanvir | |
dc.contributor.author | Mithila, Sabekun Nahar | |
dc.date.accessioned | 2023-04-03T06:47:39Z | |
dc.date.available | 2023-04-03T06:47:39Z | |
dc.date.copyright | 2022 | |
dc.date.issued | 2022-02 | |
dc.identifier.other | ID: 17146031 | |
dc.identifier.uri | http://hdl.handle.net/10361/18064 | |
dc.description | This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. | en_US |
dc.description | Cataloged from PDF version of thesis. | |
dc.description | Includes bibliographical references (pages 39-48). | |
dc.description.abstract | In current therapy for controlling peripheral nervous system disorders, one of the milestones
is the voltage-gated sodium channel modulators. They have higher efficacy with improved
side effects. They target the channel and their different subunits to modify the nerve impulse
by allowing sodium ions. Selective drugs and biological products are used as modulators to
limit the negative effects of disorders. Some drugs may either activate or deactivate the
channels by altering the voltage-gated sodium channels pore. Moreover, biological products
like alkaloids, marine toxins have a crucial role in understanding binding sites with actions on
the sodium channel. Researchers are investigating numerous isoform-selective drugs in
treating peripheral nervous system-related disorders. In this report, detailed information about
the modulator's ongoing research on the active field is also elucidated. | en_US |
dc.description.statementofresponsibility | Sabekun Nahar Mithila | |
dc.format.extent | 48 pages | |
dc.language.iso | en | en_US |
dc.publisher | Brac University | en_US |
dc.rights | Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. | |
dc.subject | VGSC | en_US |
dc.subject | Peripheral nervous system disorders | en_US |
dc.subject | Voltage-gated sodium channel modulators | en_US |
dc.subject | Marine. | en_US |
dc.subject.lcsh | Nervous system--Diseases. | |
dc.title | Role of voltage-gated sodium channel modulators in peripheral nervous system disorders | en_US |
dc.type | Thesis | en_US |
dc.contributor.department | Department of Pharmacy, Brac University | |
dc.description.degree | B. Pharmacy | |