In-vitro antioxidant and cytotoxicity screening of ethanolic extract of lagerstroemia thorelli (Lythraceae) leaves
| bracu.degree.level | Undergraduate | |
| bracu.type.group | Student Works | |
| datacite.rights | Open Access | |
| dc.contributor.advisor | Sharmin, Shahana | |
| dc.contributor.author | Tipu, Amir Hamja | |
| dc.contributor.department | School of Pharmacy | |
| dc.date.accessioned | 2024-01-30T06:31:53Z | |
| dc.date.available | 2024-01-30T06:31:53Z | |
| dc.date.copyright | 2023 | |
| dc.date.issued | 2023-02 | |
| dc.description | Cataloged from PDF version of thesis. | |
| dc.description | Includes bibliographical references (pages 47-50). | |
| dc.description | This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. | en_US |
| dc.description.abstract | "Substantial antioxidant activity of Lagerstroemia thorelli leaves extract was revealed in DPPH free radical scavenging assay with an IC50 value of 83.05085 μg/mL compared to that of 47.55245 μg/mL demonstrated by ascorbic acid. Besides, the total phenolic content test exhibited concentration of phenolic compounds in the extract to be 122.6309 mg/g GAE of dry extract. Afterwards, cytotoxicity of the extract was assessed in terms of LC50 value. During the brine shrimp lethality bioassay, cytotoxicity of the leaf extract was evaluated to be impotent based on the LC50 at 28861.40 μg/mL against that of 0.000145 μg/mL for vincristine sulfate. However, more advanced researches must be performed to discover other pharmacological properties of L. thorelli. Conclusively, on the basis of the present preliminary study, it can be claimed that the profound antioxidant property can be utilized to treat many oxidative stress-associated diseases." | en_US |
| dc.description.degree | Bachelor of Pharmacy | |
| dc.description.statementofresponsibility | Amir Hamja Tipu | |
| dc.format.extent | 50 pages | |
| dc.identifier.other | ID 19146022 | |
| dc.identifier.uri | http://hdl.handle.net/10361/22257 | |
| dc.language.iso | en | en_US |
| dc.publisher | BRAC University | en_US |
| dc.rights | Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. | |
| dc.subject | Lagerstroemia thorelli | en_US |
| dc.subject | Ascorbic acid | en_US |
| dc.subject | Phenolic compounds | en_US |
| dc.subject | Vincristine sulfate | en_US |
| dc.subject.lcsh | Antioxidant | |
| dc.title | In-vitro antioxidant and cytotoxicity screening of ethanolic extract of lagerstroemia thorelli (Lythraceae) leaves | en_US |
| dc.type | Thesis | en_US |