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dc.contributor.authorAkter, Farhana
dc.contributor.authorHossain, M. Mahboob
dc.contributor.authorRahman, Arifur
dc.contributor.authorShaha, Mukta
dc.contributor.authorAmani, Amani El Abd Abu Amo
dc.identifier.citationAkter, F., Mahboob Hossain, M., Rahman, A., Shaha, M., & Amani, A. E. A. A. A. (2012). Antimicrobials resistance pattern of escherichia coli collected from various pathological specimens. Pakistan Journal of Biological Sciences, 15(22), 1080-1084. doi:10.3923/pjbs.2012.1080.1084en_US
dc.descriptionThis article was published in the Pakistan Journal of Biological Sciences [© 2012 Pakistan Journal of Biological Sciences] and the definite version is available at : The Journal's website is at:
dc.description.abstractIrrational use of antibiotics is common in Bangladesh. The purpose of the present study was to know the effectiveness of various commonly used antimicrobials against Escherichia coli. Antimicrobial susceptibility test was done by Disc Diffusion method. In this study, antimicrobial resistance pattern of 163 isolates of Escherichia coli collected from various pathological specimens were determined. Most of the isolates (77%) were collected from urine sample. The highest numbers of isolates were resistant to cloxacillin (96.93%) and the lowest number isolates were resistant to imipenem (5.52%). Out of 163 isolates 141 (86.5%) were resistant to ampicillin, 89 (54.60%) to ceftazidime and 88 (53.99%) to ceftriaxone. From this study, it also appears that third generation cephalosporins (ceftazidime and ceftriaxone) were more effective against the test isolates in comparison to penicillin. The present study also revealed that 113 (69.33%) isolates were resistant to ciprofloxacin, 92 (56.44%) to chloramphenicol, 121 (74.23%) to co-trimoxazole and 128 (78.53%) to nalidixic acid. To the aminoglycoside drug 58 (35.58%) isolates were resistant to gentamicin and 74 (45.40%) to netilmicin. In this study 138 (84.66%) isolates were resistant to doxycycline, 126 (77.30%) isolates were resistant to tetracycline. Four isolates showed resistance to all the antimicrobials used except to imipenem. In the present study imipenem was found to be the most effective and 154 out of 163 isolates (94.48%) were found to be sensitive and cloxacillin was least effective and only 5 out of 163 isolates (3.07%) were sensitive to this penicillinase resistant drug.en_US
dc.publisher© 2012 Pakistan Journal of Biological Sciencesen_US
dc.subjectIndscriminate use of antibioticsen_US
dc.titleAntimicrobials resistance pattern of escherichia coli collected from various pathological specimensen_US
dc.contributor.departmentDepartment of Mathematics and Natural Sciences, BRAC University

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