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dc.contributor.authorDash, Pritesh Ranjan
dc.contributor.authorSheikh, Zara
dc.identifier.citationDash P.R, Sheikh Z (2015). Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium. Journal of Pharmacognosy and Phytochemistry, 4(1): 136-139.en_US
dc.descriptionThis article was published in the Journal of Pharmacognosy and Phytochemistry [©2015 Journal of Pharmacognosy and Phytochemistry] The definite version is available at:
dc.description.abstractThe methanolic extract of the rhizome of Hedychium coronarium (Family- Zingiberaceae) was screened for the presence of various phytochemicals by standard procedures and the cytotoxic activity was evaluated by brine shrimp lethality bioassay. The present study indicates that the rhizome contain carbohydrates, flavonoids, saponins, steroids and alkaloids. In brine shrimp lethality bioassay, the extract showed potent cytotoxic action. The degree of lethality was found to be directly proportional to the concentration of the extract ranging from the lowest concentration (1.25 μg/ml) to the highest concentration (320 μg/ml). The LC50 value of the methanolic rhizome extract was 0.39 μg/ml, whereas the LC50 of the reference anticancer drug vincristine sulphate was 0.52 μg/ml.en_US
dc.publisher© 2015 Journal of Pharmacognosy and Phytochemistryen_US
dc.subjectHedychium coronariumen_US
dc.subjectBrine shrimpen_US
dc.subjectArtemia salinaen_US
dc.titlePreliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronariumen_US
dc.contributor.departmentDepartment of Pharmacy, BRAC University

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