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Application of cryo-EM method to study Covid-19 proteins
(Brac University, 2022-10)
Researchers from all around the globe are working quickly to utilize cryo-electron
microscopy (cryo-EM) to explain how the corona virus disease (COVID-19) infects
human cells, in tandem to the global community's efforts ...
Lung cancer immunosuppression and therapeutic targeting of myeloid- derived suppressor cells
(Brac University, 2022-02)
Myeloid derived suppressor cells or MDSC are immune cells derived from the common myeloid
progenitor which is able to develop erythrocytes , platelets or other granulocytes .They are
separated into two different subsets ...
Therapeutic implication of senescent cell elimination in neurodegenerative diseases
(Brac University, 2022-03)
Neurodegenerative disease is a condition where the function of the brain gets affected due to
neuronal death. Still, there is no proper way to cure this disease, but there are some drugs and
treatments that can reduce ...
SHP2 inhibitors: Recent advancements and potential breakthroughs in cancer therapy
(Brac University, 2022-03)
SHP2 (Src homology-2 domain-containing protein tyrosinephosphatase-2) works as a tyrosine
phosphatase, to eliminate tyrosine phosphorylation in the non-receptor protein to link many
oncogenic signaling pathways including ...
A review on Three-Dimensional Printing (3DP) strategies to Induce Bone Regeneration in Bone Tissue Engineering
(Brac University, 2022-02)
Three-Dimensional Printing (3DP) is an essential technology to build an ideal scaffold for bone
tissue engineering which plays an important role in improving a patient’s quality of life by
reducing bone defect. The ...
CRISPR: a revolutionary tool for modeling and treating cancer and Duchenne muscular dystrophy
(Brac University, 2022-04)
The novel CRISPR/Cas system is an effective and widely used gene-editing tool that has created the opportunity to study gene function and understand the pathogenic mechanisms underlying various genetic disorders. It has ...
Immunotherapy in the treatment of renal cancer
(Brac University, 2022-01)
Renal cancer is fourteenth most common cancer worldwide which is currently increasing in
alarming rate. Many people are dying of renal cancer every day. In this situation, finding out an
efficient treatment option has ...
Zebrafish, a model for evaluating the pharmacokinetics of the drugs a comprehensive review
(Brac University, 2022-03)
To facilitate the broad use of zebrafish in drug discovery, it is essential to know the pharmacokinetic since how the body reacts with a molecule and the drug concentration at the designated site depends on it. The potential ...
A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach
(Brac University, 2022-02)
"Parkinson’s Disease (PD) is considered as one of the highest occurring neurodegenerative
disorders. Motor complexities are the major symptoms of this disease which mainly includes bradykinesia, rigidity and tremor. ...
CRISPR/Cas9 genome editing to treat sickle cell disease
(Brac University, 2022-11)
The most prevalent inherited blood condition, Sickle Cell Disease (SCD) causes excruciating
pain, permanent organ damage including liver, heart, and kidney also causes an untimely
death. There is currently a dearth of ...