Browsing School of Pharmacy (PHR) by Title
Now showing items 473-492 of 542
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A short review on additional therapeutic effects and adverse effects of sedative and hypnotic drugs
(Brac University, 2020-01)This study was conducted to list down the adverse effects and additional therapeutic effects of sedative hypnotic drugs through reviewed articles. There are different kinds of drugs as sedative hypnotic. Benzodiazepine and ... -
A short review on novel anti-malarial Heterocyclic aromatic therapeutic agents: synthesis, efficacy and effectiveness of potential drug candidates for malaria
(Brac University, 2019-04)Malaria, a vector-borne parasitic tropical illness has exponentially become a major disease as well as life threatening if not treated with right medication. Elimination of malaria is firmly back as a mainstream policy but ... -
A short review on the phenotypic, genotypic and immunological developments for Zika virus
(BRAC University, 2018-09)Zika Virus (ZIKV) has recently received much attention right after the outbreak in America. Initially ZIKV was not considered a dangerous flavivirus as the infections were asymptomatic with only mild complications. But, ... -
SHP2 inhibitors: Recent advancements and potential breakthroughs in cancer therapy
(Brac University, 2022-03)SHP2 (Src homology-2 domain-containing protein tyrosinephosphatase-2) works as a tyrosine phosphatase, to eliminate tyrosine phosphorylation in the non-receptor protein to link many oncogenic signaling pathways including ... -
Signal detection of rhabdomyolysis and death for rivastigmine: a pharmacovigilance study
(Brac University, 2023-02)The following study utilized the Food and Drug Administration Adverse Event Reporting System (FAERS) database to determine the AChI inhibitor, rivastigmine’s effect on patient mortality as well as its side effect of ... -
Significance of using Poloxamer 407 and Lactose in ibuprofen in vitro solubility enhancement
(Brac University, 2019-08)Ibuprofen is a widely used NSAID drugs dealing with mild to moderate pain formulated in numerous dosage forms. But ibuprofen has very poor solubility in water associated with minimal drug absorption hence leading to ... -
SIRT6 and cancer stem cells: is there any implication?
(Brac University, 2022-02)Cancer resembles a genetic disease that develops due to the uncontrollable growth of cells in the host body. The most prominent cause of this fatal disease development is the presence of cancer stem cells (CSCs) arise ... -
Solid self-emulsifying drug delivery system of domperidone for improved biopharmaceutical characteristics
(Brac University, 2022-09)The aim of this study was to use a solid-self emulsifying drug delivery system (S-SEDDS) to increase the solubility and dissolution rate of Domperidone (DMP), a poorly soluble, weakly basic anti-emetic medication. ... -
Solubility enhancement of fenofibrate by solid dispersion technique
(BRAC University, 2017-10-07)Solubility of drug is an imperative factor in case of oral drug delivery system to acquire intended drug concentration in systemic circulation in order to attain an efficacious therapeutic response. One of the major ... -
Solubility of Ibuprofen with Poloxamer 407 and L-leucine in water and ethanol co-solvent
(Brac University, 2019-08)Ibuprofen is a drug with very poor aqueous solubility and high permeability. Its poor aqueous solubility is one of the major problems when formulating a dosage form with it. This study was conducted by considering its poor ... -
Solubility profile of linagliptin: designing of transdermal formulation
(Brac University, 2019-05)Diabetes mellitus is a common disease in current world and according to a report of 2013, 8.3% of total adult population is suffering from this disease, with diabetes mellitus type two making up 90% of the cases. There are ... -
Sources and effect of mercury on human health: a review
(BRAC Univeristy, 2016-09)Mercury is one of the common environmental toxicants that prevails on Earth naturally due to soil erosion and volcanic eruption. This environmental pollutant is also released due to different human activities, e.g., ... -
Sources of lead contamination and awareness among Bangladeshi women of child bearing age
(BRAC University, 2015-03)Lead is one of the oldest toxins existing in the environment because of its nature and extensive use from the ancient times. Lead is commonly known as a silent killer because, at any concentration, without any noticeable ... -
Status of cognitive decline in post covid-19 Bangladeshi patients
(Brac University, 2022-12)Coronavirus disease (COVID-19) patients had greater incidences of neurological and cognitive disorders. This research studied the link between neurological illness and Coronavirus. An investigation of the experiences of ... -
Stem cell as an option for kidney injury and transplantation
(Brac University, 2022)In the past few years, kidney disease has become a major health problem all over the world. These diseases affect more than 10% of the world's people and are getting worse all the time.Chronic kidney disease (CKD) is ... -
Stem cell in cancer disease cure vs cause
(Brac University, 2022-04)Our bodies are made up of a variety of cell types. One of them is stem cells. Stem cells divide to make daughter cells in the body and in the lab. Daughter cells can self-renew or specialize into cells that fulfill a ... -
Stem cells as therapeutic carrier in cancer treatment
(Brac University, 2021-07)Cancer is one of the leading causes of death worldwide. Traditional surgery or chemotherapy are not sufficient to remove cancer completely. Researchers are trying to find out individual pathways for targeting tumor niches ... -
A study of Osteosarcoma gene profile
(Brac University, 2020-01)Osteosarcoma is a type of bone cancer casting huge threat to the human health worldwide. It is a primary bone malignancy with a particularly high incidence rate in children and adolescents relative to other age groups. The ... -
A study of the prospects of regenerative medicine highlighting some established protocols to generate organ-specific cells
(BRAC University, 2018-07)Regenerative medicine is a prominent field of research with a potential to substitute the current treatment options. From the replacement of damaged or injured tissue/organ to the changing direction of current medicinal ... -
Study of thrombolytic and anti-arthritic activities of flacourtia jangomas fruit
(Brac University, 2023-02)One of the most important medicinal plants is Flacourtia jangomas, often known as Indian plum. It is extensively distributed in South-East Asia and Bangladesh's Chittagong Hill Tracts, Cox's Bazar, and Sylhet area and is ...