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Genetic disorders associated with mutations in bHLH transcription factors: a review
(Brac University, 2022-11)
bHLH proteins belong to a superfamily of proteins characterized by one of the largest dimerized
transcriptional proteins. The main role of bHLH protein is in the developmental processes. They
function as transcriptional ...
In silico identification of molecular mimicry between T-cell epitopes of borrelia burgdorferi and the human proteome: implications for autoimmune response in Lyme disease
(Brac University, 2022-12)
Autoimmune disorder is a dysfunctional immune system in a body, which attacks its own cells. Borrelia burgdorferi, a pathogenic bacterium, shares an intrinsic relation to Lyme disease in humans causing autoreactive responses ...