Antioxidant and hypoglycemic effect of Nypa Fruticans wurmb fruit shell
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Date
2024-01Publisher
Brac UniversityAuthor
Alam, Saosan SalminMetadata
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Plant extract-based natural medicines are becoming more and more popular as a substitute for
synthetic drugs, which raises safety concerns. This study examined Nypa fruticans's
hypoglycemic and antioxidant impact. We have chosen to assess the antioxidant and
hypoglycemic qualities of the methanolic extract of N. frutican’s fruit shell (MNF) to
demonstrate this. So, DPPH (1, 1 diphenyl-2-picryl hydrazyl) test was done for the percentage
scavenging of methanolic extract of N.fruticans in contrast to Ascorbic acid for antioxidant
activities This study shows that the N.fruticans fruit shell sample's methanolic extract has an
IC50 value of 50.59 g/ml, which is indicative of its antioxidant properties, compared to the
potent antioxidant ascorbic acid's IC50 value of 44.11 g/ml. Swiss albino mice were given 10%
glucose solution as a reference medication and allowed to undergo the Oral glucose tolerance
test (OGTT) for one to three hours. Following an hour, the NFS600 glucose level declined to
12.17±2.36, which is almost identical to the usual 8.58±1.84. The remaining outcomes
followed one another. Because of this, the methanolic shell of N. fruticans has antioxidant and
hypoglycemic properties that may help advance medical research in the area of diabetes
diagnosis.