dc.contributor.advisor | Omer, Humair Bin Md. | |
dc.contributor.author | Bahar, Nazia Binta | |
dc.date.accessioned | 2023-12-18T06:03:54Z | |
dc.date.available | 2023-12-18T06:03:54Z | |
dc.date.copyright | 2023 | |
dc.date.issued | 2023-07 | |
dc.identifier.other | ID 19346021 | |
dc.identifier.uri | http://hdl.handle.net/10361/22001 | |
dc.description | This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. | en_US |
dc.description.abstract | Cancer is known as one of the world’s deadliest diseases characterized by uncontrolled cellular
proliferation. Alkylating agents are one class of anticancer drugs which cross-link DNA strands
and induce cell death. The ultimate objective of alkylating agents is to enhance patient outcomes
and lessen the impact of cancer on society. In this review article, a thorough overview of
alkylating agents utilized in cancer treatment is covered. It will discuss mechanism of actions,
structure-activity relationships (SARs), synthesis, and potential future direction of alkylating
agents. Specifically, alkylating agents that are historically important, currently used or seem
promising in clinical trials are mainly discussed here. The objective of the review is expected to
aid pharmacologists, synthetic and medicinal chemists and other healthcare professionals who are
working in the field of antineoplastic drugs to provide a state-of-the-art knowledge in making
these drugs, mechanisms of actions and its synthetic procedures in the literature. | en_US |
dc.description.statementofresponsibility | Nazia Binta Bahar | |
dc.language.iso | en | en_US |
dc.publisher | Brac University | en_US |
dc.subject | Anticancer drug | en_US |
dc.subject | Alkylating agents | en_US |
dc.subject | Mechanism of action | en_US |
dc.subject | Synthesis | en_US |
dc.title | An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis | en_US |
dc.type | Thesis | en_US |
dc.contributor.department | School of Pharmacy, Brac University | |
dc.description.degree | B. Pharmacy | |