dc.contributor.advisor | Yasmin, Hasina | |
dc.contributor.author | Trisha, Rabeya Rahman | |
dc.date.accessioned | 2022-11-17T06:17:46Z | |
dc.date.available | 2022-11-17T06:17:46Z | |
dc.date.copyright | 2022 | |
dc.date.issued | 2022-03 | |
dc.identifier.other | ID: 17346017 | |
dc.identifier.uri | http://hdl.handle.net/10361/17583 | |
dc.description | This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. | en_US |
dc.description | Cataloged from PDF version of thesis report. | |
dc.description | Includes bibliographical references (pages 31-40). | |
dc.description.abstract | Cryo-EM is a type of electron microscope that employs the cryomicroscopy technology, which
involves cooling materials and examining them under a microscope to create 3D models of
proteins. Throughout this COVID-19 pandemic, the development of medicines are critical, and
the protein structures of the SARS-CoV-2 virus must be recognized in order to battle COVID 19. Cryo-EM may be used to find protein structural alignments, protein positioning, domain motif interaction with known antiviral medications, and potential therapeutic routes for
creating treatments and vaccines. Furthermore, because Cryo-EM allows scientists to examine
dynamic models of proteins, it makes it simpler for them to analyze molecules of various shapes
and dimensions, which may be a significant benefit over X-ray crystallography. The use of
Cryo-EM in medication development for COVID-19 including how future drugs can be
designed to counter COVID-19 are discussed in this review paper so that the pandemic can be
brought to a close. | en_US |
dc.description.statementofresponsibility | Rabeya Rahman Trisha | |
dc.format.extent | 40 Pages | |
dc.language.iso | en_US | en_US |
dc.publisher | Brac University | en_US |
dc.rights | Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. | |
dc.subject | Drug Discovery | en_US |
dc.subject | Cryo-EM | en_US |
dc.subject | SARS-CoV-2 | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Drug-Protein interactions | en_US |
dc.subject.lcsh | Electron microscopy--Technique | |
dc.title | Cryo-EM in COVID-19 drug invention and discovery | en_US |
dc.type | Thesis | en_US |
dc.contributor.department | Department of Pharmacy, Brac University | |
dc.description.degree | B. Pharmacy | |