Screening of anthelmintic activity of Heritiera fomes
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Date
2022-03Publisher
Brac UniversityAuthor
Riya, Fahmida HaqueMetadata
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Heritiera fomes is a mangrove medicinal plant which is rich of ethnomedicinal usage against
helminths. At present, it is found that H. fomes is a good reservoir of compounds such as
phenols, tannin, alkaloids which have the possibility to be a better source to treat helminthiasis
in living organism which is a great motivation to work on this research. The moto of this finding
is to check in vitro anthelmintic activity of different parts (leaf, bark, root) of H. fomes on
Bangladeshi earthworms Pheretima posthuma. Albendazole was used as standard drug to
compare the test result. Anthelmintic activity was showed by three concentrations of H. fomes
(25mg/ml, 50mg/ml and 75mg/ml) of each extract in a dose dependent inhibition. The results
have been interpreted as paralysis time and death time of the earth worms. From the obtained
result it was found that bark extracts of H. fomes exhibited significant anthelmintic activity at
the concentration of 75mg/ml where the paralysis time and death time of the worms is
37.67±2.52 min and 47.67±3.51 min respectively, compared to the standard albendazole. This
study encapsulates the significance of H. fomes in the use for anthelmintic activity and
requirement further investigation for the isolation of active constituent which is responsible for
the anthelmintic activity.