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dc.contributor.advisorChoudhury, Dr. Naiyyum
dc.contributor.advisorAhsan, Dr. Chowdhury Rafiqul
dc.contributor.authorHalder, Luke Donald
dc.date.accessioned2011-11-28T04:11:30Z
dc.date.available2011-11-28T04:11:30Z
dc.date.copyright2011
dc.date.issued2011-06
dc.identifier.otherID 09276001
dc.identifier.urihttp://hdl.handle.net/10361/1497
dc.descriptionThis thesis report is submitted in partial fulfillment of the requirement for the degree of Masters of Science in Biotechnology, 2011
dc.descriptionCataloged from PDF version of thesis report.
dc.description.abstractAntibacterial and antioxidant potentials of Adiantum capillus-veneris, Blumea lacera, Cassia alata, and Cissus quadrangularis from Faridpur, Bangladesh was investigated in this study along with their toxicological evaluation. Plant materials were extracted with organic solvents (chloroform and methanol) using Soxhlet extractor. Inhibitory action of methanol and chloroform extracts of selected plants against three Gram-positive clinical isolates ¬Staphylococcus aureus, Bacillus subtilis, Bacillus cereus and three Gram-negative clinical isolates - Escherichia coil, Vibrio cholerae, Salmonella typhi was studied using agar disk diffusion, agar well diffusion methods. Broth microdilution method was utilized against Escherichia cols 0157:H7 strain and clinical isolate of Staphylococcus aureus to define the minimum inhibitory concentration of methanol extracts of selected plants. Antioxidant potential of methanol extracts of selected plant was studied using DPPH free radical scavenging assay. Morphological study of methanol extract treated distal kidney (MOCK) cell line revealed the toxicological susceptibility. Investigated plants showed no antibacterial activity against the tested clinical isolates. Significant antioxidant activity was demonstrated in the methanol extracts of investigated plants. Only Cissus quadrangularis was devoid of toxic action in the cytotoxicity assay against MDCK cell line.en_US
dc.description.statementofresponsibilityLuke Donald Halder
dc.format.extent43 pages
dc.publisherBRAC Universityen_US
dc.rightsBRAC University thesis are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectBiotechnology
dc.titleEvaluation of antibacterial, antioxidant and toxicological activity of crude extracts of Adiantum capillus-veneris, Blumea lacera, Cassia alata, and Cissus quadrangularis from Faridpur, Bangladeshen_US
dc.typeThesisen_US
dc.contributor.departmentDepartment of Mathematical and Natural Science, BRAC University
dc.description.degreeM. Biotechnology


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