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Mutation patterns in the HBB gene determine the frequency and onset of blood transfusion in patients with beta-thalassemia major and HbE-beta thalassemia
(Brac University, 2019-11)
Thalassemia is a blood disorder passed down through families (inherited) in which the body
makes an abnormal form or inadequate amount of hemoglobin. Co-inheritance of beta-thalassemia
alleles from two parents results ...
Detection of beta globin gene mutations in thalassemia patients in Bangladesh and correlation with hematological parameters
(Brac University, 2018-12)
β-thalassemia and hemoglobin E (Hb E) diseases are highly prevalent autosomal recessive disorders characterized by the reduced or absent expression of the β globin gene. β-thalassemia is now regarded as the most common ...