Browsing by Author "Hossain, M. Mahboob"
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Antibacterial and antioxidant properties of Crateva magna bark crude extract
Subarna, Rifa Tamanna (Brac University, 2023-06)Chemical compounds derived from plants have been used to treat several diseases all over the world since the dawn of human civilization. Many of the drugs that are currently on the market have either been directly or ... -
Antimicrobials resistance pattern of escherichia coli collected from various pathological specimens
Akter, Farhana; Hossain, M. Mahboob; Rahman, Arifur; Shaha, Mukta; Amani, Amani El Abd Abu Amo (© 2012 Pakistan Journal of Biological Sciences, 2012)Irrational use of antibiotics is common in Bangladesh. The purpose of the present study was to know the effectiveness of various commonly used antimicrobials against Escherichia coli. Antimicrobial susceptibility test was ... -
Binding of desloratadine and atenolol with bovine serum albumin and their in-vitro interactions
Shihab-us-Sakib, Khondoker; Islam, Mohammad A.; Moniruzzaman, M.; Hussein, Anwar; Hossain, M. Mahboob; Mazid, Mohammad A. (© 2012 Ars Pharmaceutica, 2012)Aims: The binding of atenolol a selective β1 receptor antagonist and desloratadine, an H1 receptor antagonist, to bovine serum albumin. Methods: The analysis of binding was studied by equilibrium dialysis method (ED) using ... -
Characterization of bacteria isolated from fermented food and evaluation of their potential to be probiotic
Archi, Shucheta Nazia; Tabassum, Nafisa; Juhana, Juairiah Bakth (Brac University, 2023-08)This study aimed to isolate and biochemically characterize bacteria that are not exclusively LABs from popular fermented food products and evaluate their potential to be probiotics. As primary screening, isolated bacterial ... -
Combined effect of Cefixime and Azithromycin against multiple antibiotics resistant Klebsiella pneumoniae and Pseudomonas aeruginosa
Salahuddin, Fariba (Brac University, 2019-12)Pneumonia is a lung infection with a variety of possible causes. It can be a severe disease with an infection of bacteria, virus or fungus. The lungs are inflamed and the tiny air sacs become filled with fluid inside. ... -
The combined effect of Levofloxacin and Azithromycin against multidrug-resistant Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa.
Belal, Progga Parmita (Brac University, 2022-11)Pneumonia affects everyone, particularly young children under the age of five. Acinetobacter baumannii, Klebsiella pneumonia, and Pseudomonas aeruginosa are one of the main causes of pneumonia as they cause a wide range ... -
The combined effect of Moxifloxacin and Ciprofloxacin against multidrug-resistant Klebsiella pneumoniae
Hossain, Mehrin; Chakrabortty, Deepita (Brac University, 2022)People, particularly children under the age of five suffer from pneumonia. One of the supreme pathogens of Pneumonia is Klebsiella pneumoniae which needs to be treated but it’s being burdensome because organisms are getting ... -
Detection of new Delhi Metallo-β-lactamase-1 (NDM-1) gene from multidrug-resistant pseudomonas aeruginosa isolated from Dhaka Medical College Hospital
Amin, Md. Ruhul (BRAC, 2018-12)New Delhi Metallo-beta-lactamase-1 (NDM-1) producing superbugs create a global public health problem because of their resistance to most of the antibiotics. This study was conducted to determine the presence of NDM-1 ... -
Detection of possible mutations in gyrA gene of ciprofloxacin-resistant Pseudomonas aeruginosa isolates from patients with lung infection
Mouly, Tonima Fairooz (BRAC University, 2018-07)Chronic obstructive pulmonary disease (COPD) and nosocomial pneumonia are the most frequent and persistent lung infections. Chronic obstructive pulmonary disease (COPD) and pneumonia have become the leading cause of child ... -
Development of Tetra-primer ARMS PCR based genotyping method for A clinically important SNP CYP2C19*3 (rs4986893)
Rahman, Wasifa Ar (Brac University, 2020-08)Treatment of a particular disease with satisfactory outcome has become quite a rare and challenging issue nowadays. This issue is mostly responsible for the polymorphism in the metabolizing gene which alters its metabolized ... -
Effectiveness of vitamin C on biofilm formation by clinical isolates of Pseudomonas aeruginosa
Cynthia, Syeda Sadia Akther; Tasnim, Homaira (Brac University, 2023-08)The experiment started with collecting samples of Pseudomonas aeruginosa from a clinical source of burnt patients and storing them in T1N1 media at room temperature. For confirmation of identification of the supplied ... -
Effectiveness of water filters used in the households of Dhaka city
Proma, Musharrat Shobnom; Oieshee, Monisha Hossain; Saifullah, Khaled; Tasnim, Jarin (Brac University, 2023-07)This research aims to determine the microbiological quality of tap and filtered water and figure out the efficiency of filters used in the households of Dhaka city. To start, 51 individual samples of tap and filtered water ... -
Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method
Tahsin, Anika (Brac University, 2020-08)Pharmacogenetics is the study of how similar drugs affect different people differently according to their unique genetic makeup as an individual. Pharmacogenetics includes a wide variety of research and discovery ... -
Identification of the multi-drug resistant genes in the bacteria isolated from the saliva of smoker oral cancer patients and comparative analysis with smoker normal individuals
Hasan, Samir; Siddique, Naisa; Alisa, Airina Jahan (Brac University, 2023-08)Cancer poses a severe threat to world health in the modern period. Cancer is abnormal cell proliferation that can affect different bodily components. Due to cultural behaviors like tobacco consumption and betel nut chewing, ... -
Immunoinformatics approaches towards developing vaccine/therapeutic agent against the Middle East Respiratory Syndrome Coronavirus by targeting nsp3 protein
Tanvir, Niaj Mohammad (Brac University, 2019-03-28)MERS coronavirus is an emerging virus which causes Middle East respiratory syndrome. MERS outbreak has been appearing in 27 different countries over a span of around six years with a mortality rate greater than 35% and ... -
An in silico approach for the identification of clinically significant SNPs in a Drug Metabolizing Gene CYP2C9 and development of Tetra-primer ARMS PCR based genotyping method for CYP2C9*3 (rs1057910)
Ahmed, Rifaquat (Brac University, 2020-08)The role of SNP is an important factor related to drug metabolism. The presence or absence of SNP can significantly alter the effect of the same amount of drug inside the body leading to various unwanted side-effects which ... -
In vitro collateral sensitivity: a potential approach against multiple antibiotic resistant bacteria
Yousha, Nasrat Ahmed; Badhan, Sadia Islam; Dina, Shatabdi Deb; Ahsan, MD Jahid (Brac University, 2023-07)Antimicrobial Resistance (AMR) has long been recognized as a major issue. With the emergence and rapid spread of antibiotic-resistant bacteria, the world's stock of viable antibiotics is rapidly depleting. In this regard, ... -
Investigation of insulin promoter factor 1 gene C18R and R197H variants association with type 2 diabetes mellitus in Bangladeshi population
Eusufzai, Tasnin Khan (Brac University, 2019-07)Diabetes Mellitus (DM) is a common metabolic disorder, resulting from defects in insulin secretion, insulin action, or both. But the molecular mechanism behind the basic defects of DM is not yet fully understood. Defect ... -
Isolation and characterization of Saccharomyces cerevisiae for the production of ethanol from organic sources
Rahman, Shafkat Shamim (BRAC University, 2013-10-07)Microbial production of ethanol is a very popular concept in respect of alleviating energy demand nowadays. In this regard, two fermenting strains of Saccharomyces cerevisiae were isolated from date-juice and grapes and ... -
Isolation and study of the optimum growth conditions of diesel degrading bacteria from soil
Naila, Tasmin (BRAC University, 2015-04)The rise in industrialization and globalization has made oil spills an environmental threat all over the world. Bioremediation can be considered as an effective aid to the clean-up process of spilled oil aside from expensive ...