Repairing the brain with Mesenchymal stem cells for stroke recovery

Abstract

Worldwide, stroke isthe most frequent cerebrovascular infarction causing death and disability. Despite advancements in Surgical and pharmacological treatments, therapy of neurological restoration after a stroke goes minimal, resulting in a significant reduction in quality of life. Two procedures have been approved by the Food and Drug Administration (FDA): intravenous thrombolytic therapy and endovascular thrombectomy. However, because of the tight therapeutic window, only a small fraction of stroke patients receives these therapies. Due to their potential to reverse the neurological consequences, advances in stem cell treatment have given patients with stroke fresh hope. Various kinds of stem cells have been utilized to treat stroke experimentally in animal experiments and clinical studies throughout the last few decades, from which mesenchymal stem cells have shown the most promising and safe results.