Overview on neuropeptides

Abstract

Neuropeptides are short sequences of amino acids which act on G protein couple receptors that work either directly or indirectly to function synaptic activity. According to the research neuropeptides are wide ranging as well as various categories of signaling molecules of our brain. Neuropeptides can also act as neurotransmitters, carry out neurotransmission. Neuropeptides are involved in various activities like pain management, depression, seizure activity, addiction, skin disease etc. Neuropeptides are one of the most diverse classes of signaling molecules which has a great interest in disease treatment. Neuropeptides are safer than bioactive molecules like proteins and monoclonal antibodies due to their less side effects and simple chemical modifications. There has been much progress in the field of neuropeptides. Few Peptide receptors have been identified, new drugs have been developed and novel insights into the regulation of peptide synthesis have been obtained. Though, the specific physiological roles of neuropeptides are needed to be researched.