Risk of cancer associated with antihypertensive drugs

Abstract

Antihypertensive medications are commonly used to treat hypertension, heart failure, and, more recently, cardiovascular risk reduction. Antihypertensive medicines have been implicated in the control of cell proliferation, tumor growth, and even malignancy in animal studies. The focus of this research is to look at the relationship between cancer and prior use of antihypertensive medication, taking into consideration the kind of hypertension medication and the occurrence of cancer in men and women. I obtained the signal data from the WHO Global Pharmacovigilance database VigiBase, which is accessible to the general public via the web application VigiAccess. To perform my research, I employ the PRR and chi-square methods. We have chosen several antihypertensive medications from various classifications. According to this pharmacovigilance investigation, all antihypertensive medications are not linked to cancer. However, several antihypertensive medicines with a substantial number of reports have the risk of this connection.