Phytochemical and pharmacological evaluation of Crassocephalum crepidioides

Abstract

In the development of modern medicine, the natural sources have been introduced because of their bioactive compounds and pharmacological effects. The herbs and plants are producing secondary metabolites from which semi synthesized or synthesized drugs are manufactured. Hence, the phytochemical screening of the plant Crassocephalum crepidioides was carried out to evaluate the antioxidant property in which DPPH assay and total phenolic content were measured. Besides, thrombolytic activity was conducted and to determine the toxicity of the plant brine shrimp lethality test was done. The study revealed, the moderate antioxidant effect in which the value was 637.22 in total phenolic content and in DPPH assay the half maximal inhibitory value is 136.016. At the same time, the toxicity of the plant was also moderate. Brine shrimp lethality test was performed to find out the toxicity level. However, the plant confirmed a satisfactory outcome of thrombolytic activity in which clopidogrel bisulphate was used as reference. It can be concluded that drugs can be prepared by the phytochemical screening of the methanolic extract of the plant Crassocephalum crepidioides.