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Design and development of a novel medical device using laser molding technology

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BRAC University

Citation

Abstract

Recently the outbreak of the novel coronavirus drew the attention of each corner of the world. Till now many countries are trying to develop many antiviral drugs or vaccine for the novel coronavirus. Recent news has been published (2020) that showed that this deadly virus has spread in the China. Transdermal delivery is an appropriate route for the delivery of antiviral drugs or vaccine by using the micro-needle as a tool. In this research, a laser-engineered microneedle mold was fabricated on a biocompatible acrylic sheet using a laser of CO2. The optimized mold was tested for its characterization and efficiencies. Furthermore, the characterization tests were run on the fabricated microneedle using polymer and a breakthrough result has been achieved. An animal trial also being done already this gives a significant result about the skin penetration and delivery efficiency. Manufacturing a cost-effective delivery device will be great relief in this case. The laser engraved mold can be used to fabricate any desirable depth of microneedle which can be so useful for any antiviral drug or vaccine. Finally, this cost-effective molding technique can enable the delivery of transdermal drugs in a completely new role.

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Description

Cataloged from PDF version of thesis report.
Includes bibliographical references (pages 37-48).
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.

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Type

Thesis