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Zebrafish, a model for evaluating the pharmacokinetics of the drugs a comprehensive review

bracu.degree.levelUndergraduate
bracu.type.groupStudent Works
datacite.rightsOpen Access
dc.contributor.advisorMomtaz, Tanisha
dc.contributor.authorIslam, Ashraful
dc.contributor.departmentDepartment of Pharmacy
dc.date.accessioned2022-09-26T05:50:13Z
dc.date.available2022-09-26T05:50:13Z
dc.date.copyright2022
dc.date.issued2022-03
dc.descriptionCataloged from PDF version of thesis report.
dc.descriptionIncludes bibliographical references (pages 38-41).
dc.descriptionThis thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.en_US
dc.description.abstractTo facilitate the broad use of zebrafish in drug discovery, it is essential to know the pharmacokinetic since how the body reacts with a molecule and the drug concentration at the designated site depends on it. The potential effect of a molecule can be revealed in a short time through zebrafish with high accuracy and precision. Zebrafish is considered the second most popular animal in research however; a limited scope of zebrafish research is currently available in Bangladesh. More research is required focusing on zebrafish-based pharmacokinetics, toxicology, gene editing studies to extrapolate the conducted data into mammalian models. This review summarizes the recent research that has been conducted on zebrafish whether from current medicine or xenobiotics: environment contaminants, crude chemicals, etc. to demonstrate and compare the working procedure and extrapolation on human model.en_US
dc.description.degreeBachelor of Pharmacy
dc.description.statementofresponsibilityAshraful Islam
dc.format.extent41 pages
dc.identifier.other17346057
dc.identifier.urihttp://hdl.handle.net/10361/17305
dc.language.isoenen_US
dc.publisherBRAC Universityen_US
dc.rightsBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectZebrafishen_US
dc.subjectPharmacokineticsen_US
dc.subjectAbsorptionen_US
dc.subjectDistributionen_US
dc.subjectMetabolismen_US
dc.subjectExcretion xenobioticsen_US
dc.subject.lcshZebra danio--Genetics
dc.subject.lcshDrug development
dc.titleZebrafish, a model for evaluating the pharmacokinetics of the drugs a comprehensive reviewen_US
dc.typeThesisen_US

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