Antioxidant and hypoglycemic effect of Flacourtia jangomas

Abstract

Flacourtia jangomas known as lukluki fruits is assuming to have antioxidant and hypoglycemic profile. In order to prove that, we have chosen the methanolic extract of Flacourtia jangomas fruits for assessing the antioxidant and hypoglycemic activity. So, DPPH (1, 1 diphenyl-2-picryl hydrazyl) test was done for percentage scavenging of methanolic extract of F.jangomas in contrast to Ascorbic acid for antioxidant activities. This study found that the IC50 value for methanolic extract of F.jangomas fruits was 53.71μg/ml as compared to strong antioxidant ascorbic acid IC50 46.71μg/ml which is indicator towards its antioxidant properties. In terms of hypoglycemic study, oral glucose test was conducted for 1-3 hours on swiss albino mice taking 10% glucose as a reference drug and the declination of glucose level for MFJ600 is 11.17±2.36g which is close to standard 9.48±1.84g after 1 hour and the rest of the result were sequential. So, Flacourtia jangomas fruit has antioxidant and hypoglycemic properties which may direct revolution in medicinal science in assessing diabetes.