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Antimicrobial peptides in skin diseases

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Files

18146038_PHR.pdf (1.2 MB)

Date

2022-03

Publisher

BRAC University

Authors

Full item page

URI

http://hdl.handle.net/10361/17249

Citation

Abstract

Skin diseases, including inflammatory and infections, result from disruptions in the skin's barrier. Antimicrobial peptides (AMPs) have recently gained attention as potential treatments for inflammatory, soft skin tissue and wound infections. This review discusses AMPs in skin diseases. It highlights the therapeutic properties of AMPs and their potential utility in treating skin disorders. Even though only a few AMPs, such as oritavancin and daptomycin, have been approved for use in clinical trials. Moreover, omiganan, pexiganan, and DPK-060 have also been studied extensively for treating skin problems. This paper also mentions some strategies to increase AMPs' clinical trial success rate.

Keywords

Skin diseases, inflammatory disease, Soft skin tissue infections, Antimicrobial peptides, Therapeutic agents

LC Subject Headings

Skin--Diseases, Peptide antibiotics

Description

Cataloged from PDF version of thesis report.
Includes bibliographical references (pages 45-52).
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.

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Department

Department of Pharmacy

Type

Thesis

Collections

Project report & Thesis (Bachelor of Pharmacy)