Dendritic cell vaccine for the treatment of cancer
| bracu.type.group | Student Works | |
| dc.contributor.advisor | Alam, Ms. Marzia | |
| dc.contributor.author | Haque, Tanzila | |
| dc.contributor.department | Department of Pharmacy | |
| dc.date.accessioned | 2023-01-18T09:57:24Z | |
| dc.date.available | 2023-01-18T09:57:24Z | |
| dc.date.copyright | 2022 | |
| dc.date.issued | 2022-02 | |
| dc.description | Cataloged from PDF version of thesis. | |
| dc.description | Includes bibliographical references (pages 32-38). | |
| dc.description | This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. | en_US |
| dc.description.abstract | Dendritic cells (DCs) serve as sentinels for the immune system, antigen-specific immune responses are initiated and regulated. Cross-priming, a mechanism in which DCs activate CD8 T cells by presenting external antigens to their major histocompatibility complex is crucial for CD8 T cell immunity and tolerance. Immunosuppression caused by tumors and the functional restriction of routinely utilized dendritic cells generated from monocytes are two important obstacles to the effectiveness of DC-based vaccinations. Exosomes generated from DC have piqued interest as cell-free therapeutic agents due to being inert vesicles, they are resistant to tumor-mediated suppression. Another fascinating breakthrough is the utilization of DCs that circulate naturally rather than in vitro grown DCs, which has demonstrated encouraging effects in clinical trials with both human blood cyclin dependent kinase and plasmacytoid DCs. | en_US |
| dc.description.degree | Bachelor of Pharmacy | |
| dc.description.statementofresponsibility | Tanzila Haque | |
| dc.format.extent | 38 Pages | |
| dc.identifier.other | ID: 18146090 | |
| dc.identifier.uri | http://hdl.handle.net/10361/17765 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | BRAC University | en_US |
| dc.rights | Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. | |
| dc.subject | DCexos | en_US |
| dc.subject | Plasmacytoid DC | en_US |
| dc.subject | Dendritic cell | en_US |
| dc.subject | Immunity | en_US |
| dc.subject.lcsh | Immunotherapy. | |
| dc.subject.lcsh | Cancer--Treatment. | |
| dc.title | Dendritic cell vaccine for the treatment of cancer | en_US |
| dc.type | Thesis | en_US |