An in-vitro study on anti-inflammatory properties of Alcea rosea

Abstract

Methanol extract of leaves of Alcea rosea (Family: Malvaceae) was assessed for its anti-inflammatory activity by in-vitro method. The present study focuses on the investigation of anti-inflammatory activity of methanolic extract of Alcea rosea by observing percentage (%) inhibition of haemolysis. In-vitro anti-inflammatory activity was evaluated by using membrane stabilization activity at different concentrations. Aspirin was used as a standard drug and for control normal saline was used. The result showed that Alcea rosea methanol extract at a concentration range of 100-500 μg/mL has different inhibitory action. At the concentration of 400 and 500 μg/mL the inhibition was more (13 and 14.5%). Heat induced haemolysis of erythrocyte was effective in inhibition at the concentration of 400 and 500 μg/mL. The results obtained in the present study indicate that methanol extract of the leaves of Alcea rosea have effective anti-inflammatory activity which needs further investigation.