Importance of biologically active agents over other therapies in Rheumatoid Arthritis- a review

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease which causes chronic inflammation and joint pain and will eventually lead to serious damage in the bone and cartilage of the affected joint. Many people around the world develop RA in older age. RA usually affect the joints like- elbow, shoulder and metacarpophalangeal joints in the patient. Previously with conventional therapy only the symptoms of RA was treated. However, now-a-days with biological disease-modifying anti rheumatic drugs (bDMARDs) the reason for causing RA is treated by targeting the biological receptors like- TNF-alpha, IL-1 and IL-6 etc. In this review article we are reviewing the benefits of using biological disease-modifying anti rheumatic drugs over the conventional treatment of RA.