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Evaluation of anti-microbial activity and minimum inhibitory concentration of Flacourtia jangomas fruits

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BRAC University

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Abstract

The objective of this study was to determine the particular antibacterial components of Flacourtia jangomas fruit. The antimicrobial screening used the Kirby-Baurer disk diffusion technique and the Broth dilution method, both of which are considered "standard procedures." Kirby-Baurer disk diffusion technique shows that at a concentration of 500g/disc, methanol extract demonstrated exceptional efficacy against the vast majority of test microorganisms. Bacillus cereus QL 29 performed the best among the test organisms, whereas Sacharomyces cerevaceae* fungus exhibited the least susceptibility to the extract. In Minimum Inhibitory Concentration test highest MIC value is 256 μg/ mL which shows 7 bacteria and lowest MIC result is 128 μg/ mL which is showed by 5 bacteria where the test was done on 12 bacteria. The Flacourtia jangomas fruit has been shown to exhibit significant antibacterial activity in both method.

Description

Cataloged from the PDF version of thesis.
Includes bibliographical references (pages 23-24).
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.

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Thesis