A comprehensive review on investigations of chronic neurogenetical impact of SARS-COV-2

Abstract

The emergence of the SARS-CoV-2 virus and the ensuing COVID-19 pandemic has raised concerns beyond the immediate respiratory symptoms. A growing body of evidence suggests persistent neurogenetic impacts following viral exposure, prompting the need for a comprehensive review. This review provides a meticulous analysis of existing studies of Retromer, Vacuolar ATPases, Commander, Arp2/3 Complex, Trem2, Ifitm3, Gfap, Map2, Synapsin II (Syn2) and their enduring neurogenetic consequences of SARS-CoV-2 infection, with a specific focus on long-term conditions. Additionally, this review delves into the protracted consequences of COVID-19 on neurogenetic performance, mental health, and potential connections to neurodegenerative disorders. This comprehensive assessment underscores the urgent need for continued investigation into the neurogenetic impact of SARSCoV- 2. It emphasizes the importance of ongoing surveillance and the development of therapeutic interventions to mitigate potential neurogenetic sequelae. A comprehensive understanding of these consequences is crucial for optimizing patient care and informing public health strategies in the post-pandemic landscape.