Phytochemical screening and biological activities evaluation of Chassalia curviflora

Abstract

The recent study was done to investigate the presence of phytochemical components and biological activities of the Chassalia curviflora whole plant petroleum ether, ethyl acetate and methanol extract. This study was also performed to compare the potency of the plant extract of different solvents as different phytochemical components are found in different solvent extract. The primary objective of the study was to establish this plant as a potential therapeutic agent in traditional practice of medicine in Bangladesh. In this study, disk diffusion method was used to observe antimicrobial activities of the plant extracts of different solvents. Next, DPPH (2,2-diphenyl-1-picrylhydraziyl) free radical scavenging assay, total phenolic content and total flavonoid content were done to determine the in-vitro antioxidant activity of the extract. Finally, the cytotoxic activity was determined by the use of brine shrimp lethality test and calculation of LC50 value was done to compare with the standard.