A review in nanoparticles based treatment approaches for skin cancer

Abstract

Skin cancer has become the fifth most often reported malignancy worldwide, impacting both the financial and global health. The statistics on skin cancer have been further worsened by manufacturing, genetic modification, and the rapidly increasing environmental changes. Many problems with cost, toxicity, and bioavailability plague current treatment methods, including surgery, radiation, conventional chemotherapy, targeted therapy, and immunotherapy. As a result, patient compliance is low and anti-skin cancer therapeutic efficacy is declining. To date, there have been a number of nanotechnological developments that have helped to overcome this limitation. Of all the nanomaterials, nanoparticles have provided enormous benefits by serving as medication carriers and therapeutic agents for the amazing treatment of skin cancer. Through their poor blood vessels, the tiny size and great surface area to volume ratio of nanoparticles lead to increased treatment efficacy by increasing the absorption of skin tumors. In this regard, the current review offers up-to-date details on the various forms and pathophysiology of skin cancer, as well as the available treatments and side effects.The role of several lipid, polymer, and inorganic nanoparticles in the therapy of skin cancer is also thoroughly examined, and their patents and clinical trials are then reported.