Phytochemical & antidiarrheal activity of Nypa fruticans wurmb fruit shell

Abstract

The objectives of this study were to determine the phytochemical composition and evaluate the potential antidiarrheal activity of the methanol extract obtained from N. Fruticans wurmb by its fruit shell. The phytochemical screening was conducted using qualitative analysis, whereas the antidiarrheal test was assessed using the castor oil induced method. Based on the findings of the phytochemical investigation, the methanol extract of the N. fruticans wurmb fruit shell included carbohydrates, saponin, resin, flavonoids, phenolic compounds, alkaloids, tannin, steroids, glycosides, and fixed oil. In the analysis of antidiarrheal activities, loperamide HCl served as the reference standard. In compared to Loperamide HCl (78.1%), diarrheic faeces were reduced at 200mg/kg, 400mg/kg and 600mg/kg with an inhibition of 23.15%, 37.49% and 59.42%. These results demonstrated the significant antidiarrheal action of the N. Fruticans wurmb methanolic shell extract.