Gut microbiology and it's relationship with cancer

Abstract

This paper explores the significant relationship between the human gut microbiome and cancer. It outlines how an imbalance in gut bacteria, known as dysbiosis. Dysbiosis can increase cancer risk, particularly in colorectal and gastric cancers, through mechanisms such as inflammation and immune modulation. The methodology involves a systematic review of literature focused on gut microbiota's influence on cancer, including data extraction, synthesis and identification of research gaps. Findings highlight specific microbial species linked to cancer progression and treatment, such as Fusobacterium nucleatum and Bifidobacterium. The discussion emphasizes the potential of personalized medicine based on gut microbiome analysis for improving cancer therapies. The conclusion calls for further research to bridge existing knowledge gaps, aiming to enhance cancer prevention strategies and treatment efficacy.