A 3D printed quick response encoded Orodispersible film for personalized medicine

Abstract

Personalization is the future of medicine for patient adherence and safety. A 3D printed QR encoded orodispersible film (3DQRODF) is an efficient alternative to usual dosage form of capsule and tablet with the potential of tailored treatment. Orodispersible Film (ODF) is compliant to patient for ease of administration without water, particularly patients with swallowing problems e.g. pediatrics and geriatrics. 3D printing is utilized for precise shape and size of ODF. Quick Response (QR) code was printed in one step process by directly feeding nozzle of hot melt extrusion (HME). QR code is designed with drug loaded encoded information and can be accessed by QR scanner with the aid of smart device. Patient specific QRODF with uniform dosing allows personalized treatment, as well as tracking of QR code can turn aside counterfeit of medicine. 3DQRODF is promising to shift the paradigm from ‗one size fits all‘ to personalization.