Phytochemical screening and antimicrobial activity of the methanolic extract of Polyalthia suberosa stem

Abstract

Polyalthia suberosa is a medicinal plant widely used in traditional Asian medicine for its anti-inflammatory, analgesic, and antimicrobial properties. Its bioactive compounds have attracted interest for potential pharmaceutical applications. The present study was conducted to find out the phytochemical constituents and antimicrobial effect of the methanolic extract of the stem part (MPSS). The phytochemical screening was performed following the standard methods. Antimicrobial activity was tested against 5 pathogenic bacteria Bacillus cereus, Bacillus subtilis, Escherichia coli, Klebsiella peunomoniae, Pseudomonas aeruginosa by the Disk diffusion method. Alkaloids, tannins, flavonoids, saponins, glycosides, phenolic compounds, steroids, and resin were some of the chemical constituents identified during phytochemical screening. The plant showed moderate antimicrobial activity in tested microorganisms. Although the experimented extract showed an antimicrobial activity against the tested pathogenic microbes. but we still don’t know which components is responsible for this effect; thus, further work regarding this can be done.