Drug repurposing: potential of Antimicrobial Drugs in Breast Cancer Treatment

Abstract

Researchers and doctors have been encouraged to repurpose currently used medications to lessen the financial burden of drug development and provide potential novel treatments because of the rising expense of drugs globally, particularly in oncology. Drug repurposing frequently causes fewer safety concerns due to the current medicines' well-established dose, safety, and toxicity profiles, which leads to faster and more successful approval of its use for new purposes. For growing resistance to the current treatments, drug repurposing represents an attractive prospect in breast cancer. It's important to note that 335 medications as repurposed drugs are now being tested in various clinical studies for their potential effects on malignancies. This review aims to provide a thorough discussion of the anti-cancer effects of antimicrobial agents and provide details on their mechanism of action. Furthermore, the challenges and potential for future development and clinical applications of current antimicrobial medications for cancer therapy are also delineated.