A review on the pharmacological effects of hormonal and antidiabetic drugs in the treatment of Polycystic Ovary Syndrome

Abstract

Polycystic ovary syndrome is one of the most common heterogenic disorder that affects 5-10% women during their reproductive age. The purpose of this project is to compare the effects of hormonal and anti-diabetic drugs associated with polycystic ovary syndrome. The effects of the anti-diabetic drugs such as metformin, pioglitazone, rosiglitazone, letrozole and hormonal drugs like ethinyl estradiol, estradiol valerate, cyproterone acetate, medroxyprogesterone acetate, deinogest, desogestrel, drospirenone on PCOS affected women have been emphasized in this investigation. In most of the cases, the combination of both hormonal and antidiabetic drugs have provided better results. This work has been focused on the laboratory assay techniques, results and discussion provided on these articles. The most advantageous effects of the available drugs have been emphasized in these work. The researchers and clinicians may be benefited from this project on the ground of selection of combination drugs for the treatment of PCOS.