A study on antibiotic resistance pattern among patients of a selected hospital in Dhaka, Bangladesh

Abstract

The recent emergence of multidrug-resistant pathogens poses a significant threat to global public health. The major objective of this study was to investigate the prevalence and antimicrobial susceptibility patterns of clinical isolates collected at a selected hospital of Bangladesh. Out of 1890 samples, only 489 showed positive for pathogens. Among the isolates, Escherichia coli (51%) was the most prevalent, followed by Staphylococcus aureus (21%), Salmonella typhi (8.6%), Pseudomonas spp. (7.2%), Acinetobacter spp. (5.3%), Streptococcus spp. (4.9%), Klebsiella spp. (1.6%) and Neisseria gonorrhoeae (0.2%). Male patients (n = 94, 19%) were found to be infected mostly with Salmonella typhi (27%) whereas female patients (n = 395, 81%) were more susceptible to E. coli (58%). Among the isolates, 83% were MDR with an MAR index of 0.03-0.45. Overall, this study provides valuable insights into the current status of antibiotic resistance and helps develop strategies for effective management and containment of MDR infections.