Review on: Cell penetrating peptide-enabled drug delivery into a targeted cell

Abstract

In the past two to three decades, researchers have looked into a variety of perspectives and methods for cell penetrating peptides-mediated drug delivery, which has formed the basis of a brilliant method for delivering drugs. Their capacity to break through cellular membranes and transport a wide variety of contents into the cells led to their selection as an ideal delivery system. Preclinical studies suggest that these chemicals may be useful in treating neurodegenerative diseases like Parkinson's and Alzheimer's since they may relatively easily breach the blood-brain barrier. Amidst that, no cpp-cargo has been approved by the FDA as of yet due to specific restrictions. However, scientists are continually attempting to overcome these constraints in order to obtain more accurate results.