A short review on additional therapeutic effects and adverse effects of sedative and hypnotic drugs

Abstract

This study was conducted to list down the adverse effects and additional therapeutic effects of sedative hypnotic drugs through reviewed articles. There are different kinds of drugs as sedative hypnotic. Benzodiazepine and z-drugs is mostly used drug among those reported by the articles. Moreover the benzodiazepine causes severe adverse effects on older adults. The article reported that about 2.6 % older adult patient were affected by hip and other bone fracture for using benzodiazepine and other sedative hypnotic drugs to treat insomnia. Moreover other articles also reported that the pregnant women also have more chance to adverse effect for using sedative hypnotic drug. On the other hand, there is report for new molecule as sedative hypnotic drug called Indiplone showed anti aggregation effect on platelet with less adverse effects. Another articles reported that sedative hypnotic drug may used as analgesic drug. In addition there are some plant extract contain alkaloids, flavanoids used as sedative drug also showed different therapeutic effects. These extractions showed anti diabetic, sleep latency property. The articles were reviewed on both qualitative and quantitative analysis as well as in-vitro and in-vivo results were analyzed.