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Oncolytic viral therapy: new horizons for cancer remedy in the 21st Century

dc.contributor.advisorAkter, Raushanara
dc.contributor.authorMondal, Yaseer Arafat A.
dc.contributor.departmentDepartment of Pharmacy
dc.date.accessioned2019-10-24T05:19:59Z
dc.date.available2019-10-24T05:19:59Z
dc.date.copyright2019
dc.date.issued2019-08
dc.descriptionCataloged from PDF version of project report.
dc.descriptionIncludes bibliographical references (pages 90-102).
dc.descriptionThis project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.en_US
dc.description.abstractOncolytic viral therapy has proven to be propitious that is making glorious inroads against the vicious claws of cancer. Oncolytic viruses (OVs) are modified to replicate in a selective manner in neoplastic cells. They crossprime antineoplastic immunity by directly obliterating infected cancerous cells to propel uninfected cancer cell annihilation. The aspiration of this arena is to generate oncolytic viruses that can be comfortably constructed, proficiently disseminated to targeted neoplastic sites, experience quick intra-tumoural dispersion, explicitly destroy tumor cells, prompt no collateral harm and represent no danger of transmission within the populace. In this review, an attempt has been made to briefly discuss about an array of virus modulations that are being sought after to optimize administration, intra-tumoural scattering and safety of OVs gleaned from various viruses. With ceaseless progression, OVs can potentially revolutionize the current paradigm of cancer therapy.en_US
dc.description.degreeB. Pharmacy
dc.description.statementofresponsibilityYaseer Arafat A. Mondal
dc.format.extent102 pages
dc.identifier.otherID 14346004
dc.identifier.urihttp://hdl.handle.net/10361/12806
dc.language.isoenen_US
dc.publisherBrac Universityen_US
dc.rightsBrac University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectTumouren_US
dc.subjectMicroenvironmenten_US
dc.subjectOncolytic virusen_US
dc.subject.lcshCancer--Treatment
dc.titleOncolytic viral therapy: new horizons for cancer remedy in the 21st Centuryen_US
dc.typeProject Reporten_US

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