A review on the novel Heterocyclic Antileishmanial drugs for the treatment of Leishmaniasis

Abstract

New antileishmanialdrugs must be developed to make the treatment of leishmaniasis available for the people all over the world. It must be ensured that every single person has access to the medicines. Alternatives to the current antileishmanials are not only necessary for the lack of availability but also necessary for another crucial problem that is the toxicity level of the current medicines. In some cases, the current antileishmanials appeared to be ineffective because parasite resistance occurred. Therefore, search for alternatives should be done so that we can use them in different clinical situations like parasite resistance and toxicity. This review was done with the aim to study newer molecules that can be used as an alternative to the current antileishmanial agents.