Preliminary phytochemical screening and biological investigation of methanol and hexane extracts of Borreria Pusilla

Abstract

Borreria pusilla is a traditional medicinal plant in Bangladesh that traditionally used to treat bone fracture. The aim of this study was to identify the phytochemical components and to investigate in vitro antioxidant and antibacterial activity of its methanol and hexane extracts. It’s phytochemical screening revealed the existence of carbohydrates, flavonoids, alkaloids, phenolic compounds and tannins in methanol extract whereas, hexane extract contained alkaloids, phenolic compounds, glycosides, carbohydrates and steroids. The plant extracts, along with its total phenolic content and flavonoid content, showed notable antioxidant activities through DPPH free radical scavenging assay. Moreover, Disc diffusion method evaluated the antimicrobial activity in which the both plant extracts mostly showed activity against the Staphylococcus aureus, Bacillus subtilis, and Enterococcus faecalis bacteria. The present data that investigated may be valuable for conducting research and developing new drugs to treat various types of diseases in our country as well as elsewhere in the world.