Animal model and recent advancement in cardiac disease treatment: a review

Abstract

Cardiovascular diseases are one of the most perilous diseases causing death throughout the world. Recent developments in the field of cardiac disease treatment are appearing through advancements in science. Significant progress has been achieved in cardiac disease therapy over the past few years such as development in new cardiac medicine, surgery, cardiac imaging and nuclear machine, cardiac electro pacing, non-invasive cardiac treatment and gene therapy etc. Animals have been emerged in history of mankind for research purpose for thousands of years. Experimental animal study gives important knowledge about cause of disease, pathogenesis, problems associated with a disease and about effectiveness and mechanism of action of different drugs and other substances intended for treatment. Animal models can be managed more efficiently than human model because animal’s nutritional and environmental characteristics are well manageable. Animal models such as rat, rabbit, guinea pig, canine and zebra fish models etc. are used in research study.