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Method development of oil solubility test of Aceclofenac

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bracu.degree.levelUndergraduate
bracu.type.groupStudent Works
datacite.rightsOpen Access
dc.contributor.advisorChowdhury, Namara Mariam
dc.contributor.authorRay, Joytee
dc.contributor.departmentDepartment of Pharmacy
dc.date.accessioned2020-08-11T11:58:18Z
dc.date.available2020-08-11T11:58:18Z
dc.date.copyright2019
dc.date.issued2019-10
dc.descriptionCataloged from PDF version of thesis report.
dc.descriptionIncludes bibliographical references (pages 34-42).
dc.descriptionThis thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.en_US
dc.description.abstractThe aim of the study was to develop a method that would allow the solubility testing of Aceclofenac in different oils. The main target was to find a suitable method by using commercially available drugs like olive oil. The process involved screening of oil after which extraction was done in a separating funnel in order to differentiate the API using hexane and methanol. The absorbance was taken in UV spectrophotometer and wavelength scan of hexane layer was found out. Series of extraction was done to see up to how many extractions were needed until there was no more API peak in the hexane layer and all the Aceclofenac was dissolved in methanol layer. The results showed that, after 10 times extraction the absorbance of the methanol layer at 277 nm came out 0.78 which falls within the ideal range 0.5-1 and no peak was seen in the hexane layer within the wavelength range.en_US
dc.description.degreeBachelor of Pharmacy
dc.description.statementofresponsibilityJoytee Ray
dc.format.extent42 pages
dc.identifier.otherID 15346016
dc.identifier.urihttp://hdl.handle.net/10361/13935
dc.language.isoenen_US
dc.publisherBRAC Universityen_US
dc.rightsBrac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectNanoemulsionen_US
dc.subjectSolubilityen_US
dc.subjectAceclofenacen_US
dc.subjectExtraction of oilen_US
dc.subjectHexane layeren_US
dc.subject.lcshMedicine
dc.titleMethod development of oil solubility test of Aceclofenacen_US
dc.typeThesisen_US

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