Role of Mesenchymal Stem Cells & MicroRNA in the treatment of Osteoporosis
Abstract
Osteoporosis is currently the most difficult and painful disease endangering the lifestyle of the
geriatric population. Through the gradual degeneration of osteoblastic cell in various parts of the
bones, osteoporosis has caused a massive healthcare problem and cost for a significant part of the
world populace. Despite having conventional therapies, like bisphosphonates, the disease still has
no sustainable treatment option because the conventional drugs only emphasize on preventing
bone degradation, not bone regeneration. As such, increasing researches on regenerative treatment
options are getting huge attention especially in mesenchymal stem cells and it’s relationship with
microRNAs. This novel treatment techniques introduces a sustainable, cost efficient and long lasting options for the osteoporotic patients. As such, this review mainly focuses on the tonsil
derived mesenchymal stem cell therapy along with the therapeutic effects of microRNA in order
to examine whether their therapeutic and regenerative potential are truly an amazing alternative or
not.