In-vitro antacid screening of methanolic leaf extracts of Elaeocarpus floribundus

Abstract

Elaeocarpus floribundus is a sort of tropical and subtropical evergreen trees and shrubs. Elaeocarpaceae is a family which has very nearly 615 types of plants in 12 genera. Among them with roughly 350 species Elaeocarpus is the biggest genera which has anti-ulcer, anti-inflammatory, anti-hypertensive, anti-diabetic, anti-bacterial property. This present study focuses on the in-vitro antacid screening of methanolic leaf extracts by doing preliminary antacid test, acid neutralizing capacity, acid neutralizing effect of extracts on GSF and lastly acid buffering capacity. Concentration of 1 mg/mL of leaf extract and 1 mg/mL of standard sodium bicarbonate was used for conducting all the tests. Methanolic extract of leaves shows very poor antacid properties. Using methanol instead of ethanol or aqueous extraction can be a reason for not showing proper result. However, a comparative study between methanolic and ethanolic extracts can be done in future to evaluate better results. Moreover, an anti-ulcer test can also be done from the leaf extracts.