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dc.contributor.advisorNeelotpol, Dr Sharmind
dc.contributor.authorMomtaz, Tanisha
dc.date.accessioned2017-02-02T07:32:04Z
dc.date.available2017-02-02T07:32:04Z
dc.date.copyright2016
dc.date.issued2016-02
dc.identifier.otherID 12146025
dc.identifier.urihttp://hdl.handle.net/10361/7728
dc.descriptionThis project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2016en_US
dc.descriptionCataloged from PDF version of project report.
dc.descriptionIncludes bibliographical references (page 38-41).
dc.description.abstractIncreasing complaints about metal toxicity have been reported with the modernization of medical science. However, in this field, aluminum has been a renewed matter of concern. Therefore, more impotence is given to find out natural as well as synthetic substances that can alleviate the toxic effect of aluminum in the body. That is why; this study has aimed to identify the effect of vitamin E in reducing the toxic effect on biological systems caused by Aluminum. The study was conducted for 28 days and with total 18 female albino Wistar rats weighing 138-150g. 18 rats were divided into three groups-control, aluminum treated and aluminum plus vitamin E treated. The control group was receiving normal drinking water along with two drops of Tween 80 whereas aluminum treated group was getting aluminum nitrate solution 1ml/rat containing half ‘x’ of body weight and two drops of Tween 80. Moreover, aluminum plus vitamin E treated group was receiving aluminum nitrate solution 1ml/rat containing half ‘x’ of body weight along with 1ml/rat vitamin containing 22.5 mg of vitamin E per kg and also two drops of Tween 80. After 28 days, the rats were sacrificed, and blood was collected from the heart using ventricular puncture method. The collected blood was sent for hematological and clinical bio-chemistry examinations. At the same time, the liver, skin, brain, kidney and ovary of the rats were collected in the formalin and sent for histopathological study. The clinical biochemistry examination showed significant results for all the parameters except basophils, while the histopathology showed that vitamin E has the potential to eliminate the toxic effects caused by aluminum.en_US
dc.description.statementofresponsibilityTanisha Momtaz
dc.format.extent41 pages
dc.language.isoenen_US
dc.publisherBRAC Universityen_US
dc.rightsBRAC University project report are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission.
dc.subjectAluminum toxicityen_US
dc.subjectFemale ratsen_US
dc.subjectBiological systemsen_US
dc.subjectVitamin Een_US
dc.titleA study on aluminum toxicity with female rats: can vitamin E help to reduce its effect on biological systems?en_US
dc.typeProject reporten_US
dc.contributor.departmentDepartment of Pharmacy, BRAC University
dc.description.degreeB. Pharmacy


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