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A pharmacovigilance study on Donepezil: signal detection of rhabdomyolysis and death
(Brac University, 2023-02)
Alzheimer’s disease is an age-related neurodegenerative disease that effects the cognitive ability of a person. The cholinesterase inhibitor “donepezil” is used to treat Alzheimer's disease. Donepezil has shown the greatest ...
Knowledge of Alzheimer’s disease and its relationship with attitude towards genetic testing for the disease: a survey of the general public in Bangladesh
(Brac University, 2022-04)
Purpose: Alzheimer's disease (AD) is a multifactorial neurodegenerative brain disorder that affects approximately 5.3 million people in the United States, including nearly half of the population aged 85 and up. It has ...
Review on: Contribution of nutrients to retard the progression of Alzheimer’s disease
(Brac University, 2022-11)
In neurology, Alzheimer's disease represents greatest unmet medical need. Formation of
neurofibrillary tangles, Amyloid Beta-peptide (Aβ) deposition, and significant oxidative
stress, synapse loss are features of the ...
A review of comparison on efficacy, safety and cost effectiveness of cholinesterase inhibitors, NMDA antagonists and combination therapy in the treatment of Alzheimer’s disease
(BRAC University, 2018-08)
Alzheimer’s disease (AD), a deadly neurodegenerative disease, which is considered as one of the top causes of death for people who are over 65 years of age. Up until now, no drug has been developed that can cure this disease ...
Bio-similar drug development and accessible drugs in the market for the treatment of Alzheimer's Disease: Current status
(Brac University, 2022-04)
A decade has passed since no new Alzheimer's disease (AD) therapies were approved, even
though it is the leading motive of dementia in the modern era. The community of patients with
AD leads to expansion. Anxiety, anger, ...
Marine compounds in the treatment of Alzheimer’s disease
(Brac University, 2022-03)
Brain shrinkage and cell death occurs due to Alzheimer's disease, a degenerative neurologic illness. Memory loss, social and behavioral deterioration, and the inability to operate independently are all symptoms of Alzheimer's ...
Emerging therapies of Alzheimer’s disease: a comprehensive review
(Brac University, 2022-11)
Alzheimer’s disease is a complex, debilitating neurodegenerative disorder, with a rapidly increasing worldwide prevalence. Despite decades of intense research, therapeutics for Alzheimer's disease are still limited to ...
Glymphatic system: a pathway for managing endogenous metabolites in CNS
(Brac University, 2017-11)
Glymphatic pathway is one of the recent discoveries of neuro pharmacology which is a brainwide
paravascular system to exchange cerebrospinal fluid (CSF) and interstitial fluid. This
system is associated with the clearance ...
Application of microRNA (miRNA) in Alzheimer’s Disease (AD)
(Brac University, 2022-03)
Alzheimer's disease is a fatal illness that primarily affects older generations; its pathology pathways include beta-amyloid, tau protein, and activated microglia, destruction of synapse and no disease-modifying medication ...
Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease
(Brac University, 2021-11)
Tau protein is one of the keystones in the diagnosis of Alzheimer’s disease. The modern detection techniques have come up to visualize, track and assess tau pathology and have further contributed with information about tau ...